A hidden brain energy signal drives depression and anxiety

Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called connexin 43, which helps release ATP, caused similar symptoms even without stress. Restoring this protein improved mood-related behavior.

A hidden brain energy signal drives depression and anxiety
Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called connexin 43, which helps release ATP, caused similar symptoms even without stress. Restoring this protein improved mood-related behavior.

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