Hidden gut cells could transform food allergy treatment

Scientists have uncovered a surprising new pathway behind life-threatening food allergies. Instead of histamine, a different chemical called leukotrienes drives severe reactions in the gut. These molecules, released by specialized mast cells, trigger inflammation and anaphylaxis when food allergens are ingested. Drugs already approved for asthma may block this pathway, opening the door to new ways to prevent or treat food-induced allergic emergencies.

Health Sep 8, 2025 0 41 Add to Reading List

Hidden gut cells could transform food allergy treatment

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Scientists have uncovered a surprising new pathway behind life-threatening food allergies. Instead of histamine, a different chemical called leukotrienes drives severe reactions in the gut. These molecules, released by specialized mast cells, trigger inflammation and anaphylaxis when food allergens are ingested. Drugs already approved for asthma may block this pathway, opening the door to new ways to prevent or treat food-induced allergic emergencies.

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