Decoding cell fate: Key mechanism in stem cell switch identified

Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, scientists identified a new gene, Daam1, that plays an essential role, switching on the development of secretory cells in the intestine. This finding opens new perspectives in cancer research.  

Decoding cell fate: Key mechanism in stem cell switch identified


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Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, scientists identified a new gene, Daam1, that plays an essential role, switching on the development of secretory cells in the intestine. This finding opens new perspectives in cancer research.  

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